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Adrian P L Smith Selected Research

flutemetamol

1/2021Visual assessment of [18F]flutemetamol PET images can detect early amyloid pathology and grade its extent.
11/2019Different aspects of Alzheimer's disease-related amyloid β-peptide pathology and their relationship to amyloid positron emission tomography imaging and dementia.
10/2018Estimation of amyloid distribution by [18F]flutemetamol PET predicts the neuropathological phase of amyloid β-protein deposition.
1/2017Performance of [18F]flutemetamol amyloid imaging against the neuritic plaque component of CERAD and the current (2012) NIA-AA recommendations for the neuropathologic diagnosis of Alzheimer's disease.
12/2016Post-mortem histopathology underlying β-amyloid PET imaging following flutemetamol F 18 injection.
8/2015[(18)F]flutemetamol amyloid positron emission tomography in preclinical and symptomatic Alzheimer's disease: specific detection of advanced phases of amyloid-β pathology.
3/2015Phase 3 trial of flutemetamol labeled with radioactive fluorine 18 imaging and neuritic plaque density.

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Adrian P L Smith Research Topics

Disease

6Amyloid Plaque
01/2021 - 03/2015
6Alzheimer Disease (Alzheimer's Disease)
01/2020 - 03/2015
5Death (Near-Death Experience)
10/2018 - 03/2015
4Dementia (Dementias)
01/2020 - 08/2015
2Cerebral Amyloid Angiopathy (Congophilic Angiopathy)
11/2019 - 12/2016
1Body Weight (Weight, Body)
01/2017
1Atrophy
12/2016
1Neurodegenerative Diseases (Neurodegenerative Disease)
12/2016
1Pituitary Neoplasms (Pituitary Adenoma)
02/2003
1Pulmonary Hypertension
03/2002

Drug/Important Bio-Agent (IBA)

7flutemetamolIBA
01/2021 - 03/2015
7Amyloid (Amyloid Fibrils)IBA
01/2020 - 03/2015
2Peptides (Polypeptides)IBA
01/2020 - 11/2019
1Proteins (Proteins, Gene)FDA Link
10/2018
1GadoliniumIBA
01/2017
1gadodiamide (Omniscan)FDA Link
01/2017
1FluorineIBA
03/2015
1phaeomelaninIBA
02/2003
1alpha-MSHIBA
02/2003
1eumelaninIBA
02/2003
1Messenger RNA (mRNA)IBA
03/2002
1Endothelin-1 (Endothelin 1)IBA
03/2002